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Annotation Overview for fig|196164.1.peg.1661 in Corynebacterium efficiens YS-314:
Aconitate hydratase (EC 4.2.1.3) @ 2-methylisocitrate dehydratase (EC 4.2.1.99)

current assignment
This feature plays multiple roles which are implemented by the same domain with a broad specificity. The roles are:
Aconitate hydratase (EC 4.2.1.3)EC Number 4.2.1.3
2-methylisocitrate dehydratase (EC 4.2.1.99)EC Number 4.2.1.99
taxonomy id196164contig
internal linksgenome browser | feature evidence | sequenceACH [?]show essentially identical genes
annotation historyrun tool
FigFamFIG138200
data base cross references
(dbxref)

This feature is part of a subsystem
  • In Glyoxylate bypass its role is Aconitate hydratase (EC 4.2.1.3).
  • In Methylcitrate cycle its role is 2-methylisocitrate dehydratase (EC 4.2.1.99).
  • In Serine-glyoxylate cycle its role is Aconitate hydratase (EC 4.2.1.3).
  • In Glyoxylate Synthesis its role is Aconitate hydratase (EC 4.2.1.3).
  • In Propionate-CoA to Succinate Module its role is 2-methylisocitrate dehydratase (EC 4.2.1.99) and Aconitate hydratase (EC 4.2.1.3).
  • In TCA Cycle its role is Aconitate hydratase (EC 4.2.1.3).
  • In Propionate-CoA to Succinate Module its role is 2-methylisocitrate dehydratase (EC 4.2.1.99) and Aconitate hydratase (EC 4.2.1.3).
  • Reasons for Current Assignment

    The encoded protein plays multiple roles which are implemented by the same domain with a broad specificity. The roles are "Aconitate hydratase (EC 4.2.1.3)" and "2-methylisocitrate dehydratase (EC 4.2.1.99)". The protein occurs in 7 subsystems: "Biogenesis of c-type cytochromes", "Glyoxylate Synthesis", "Glyoxylate bypass", "Methylcitrate cycle", "Propionate-CoA to Succinate Module", "Serine-glyoxylate cycle", and "TCA Cycle". In "Biogenesis of c-type cytochromes", it appears to play a functional role that we have not associated with any other gene. In "Glyoxylate bypass", it appears to play a functional role that we have not associated with any other gene. In "Methylcitrate cycle", it appears to play a functional role that we have not associated with any other gene. In "Propionate-CoA to Succinate Module", it appears to play a functional role that we have not associated with any other gene. In "Serine-glyoxylate cycle", it appears to play a functional role that we have not associated with any other gene. In "TCA Cycle", it appears to play a functional role that we have not associated with any other gene. The function of genes having the same functional roles have been described in Escherichia coli (10585860, 1541275, 1838390). This is a homologous protein which implements the same function.

    Compare Regions

    The chromosomal region of the focus gene (top) is compared with four similar organisms. The graphic is centered on the focus gene, which is red and numbered 1. Sets of genes with similar sequence are grouped with the same number and color. Genes whose relative position is conserved in at least four other species are functionally coupled and share gray background boxes. The size of the region and the number of genomes may be reset. Click on any arrow in the display to refocus the comparison on that gene. The focus gene always points to the right, even if it is located on the minus strand.






    Topic revision: r6 - 02 Mar 2009 - 22:06:54 - Bruce Parrello
     
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    NMPDR is a collaboration among researchers from the Computation Institute of the University of Chicago, the Fellowship for Interpretation of Genomes (FIG), Argonne National Laboratory, and the National Center for Supercomputing Applications (NCSA) at the University of Illinois. NMPDR is funded by the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, under Contract HHSN266200400042C. Banner images are copyright © Dennis Kunkel.